![]() Gaucher's disease treatments, such as eliglustat.cystic fibrosis medications, such as ivacaftor.cancer treatments, such as pomalidomide.Common medications that may interact with lidocaine include: Speak to your doctor about how drug interactions should be managed. ![]() An interaction between two medications does not always mean that you must stop taking one of the medications however, sometimes it does. Medicines that interact with lidocaine may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with lidocaine. The duration of action of lidocaine may be prolonged in people with liver disease.Higher dosages or volumes of lidocaine will result in a shorter time to the onset of anesthesia, a longer duration of effect, a greater degree of muscle relaxation, and an increase in the spread of the anesthesia.The duration of effect is approximately 60 to 90 minutes. When administered as a local or regional anesthetic, lidocaine is effective almost immediately.When used for local or regional anesthesia, a temporary loss of sensation and a restriction in the ability to move the affected body area may occur.Also, let them know if you have had recent surgery. Tell all your healthcare providers about all your medical conditions, allergies, and all the medicines you use.Lidocaine will be administered to you by a health professional.Lidocaine antiarrhythmic is used in the emergency treatment of certain heart conditions. Lidocaine is used as a local or regional anesthetic to prevent pain signals from being transmitted to the brain during surgical, dental, and other procedures. Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. May interact with some medications including beta-blockers, cimetidine, antiarrhythmics, and HIV agents.Careful dosing is required in people with liver disease. May not be suitable for some people including those with respiratory disease, cardiovascular disease, liver or kidney disease, low blood pressure, epilepsy, myasthenia gravis, or congestive heart failure.IM lidocaine may increase creatine phosphokinase levels which may compromise tests for this enzyme following an acute myocardial infarction.Local anesthetics injected into the head or neck area may produce side effects similar to systemic toxicity including confusion, convulsions, and respiratory depression.Drowsiness is usually a reflection of high blood levels of lidocaine. Side effects may be more severe with lidocaine antiarrhythmic and include lightheadedness, drowsiness, nausea or vomiting, slow heartbeat, and low blood pressure.Stop the infusion if prolongation of the PR interval and QRS complex appearance or aggravation of arrhythmias. When given to treat cardiac arrhythmias, terminate the infusion as soon as the basic cardiac rhythm appears stable or at the earliest sign of toxicity.Bruising, bleeding, swelling, and pain at the injection site are less common. Skin redness, itching, a rash, or a feeling of warmth may occur in the region where lidocaine has been administered subcutaneously when used for local anesthesia.If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include: May be given as a last resort to treat status epilepticus (lidocaine systemic).No dosage adjustment is required in renal impairment.Administer as an IV bolus for the initial treatment of ventricular arrhythmias. The IM formulation is no longer commercially available in the United States. Systemic lidocaine is administered IV.Lidocaine antiarrhythmic may be used in the emergency treatment of cardiac arrest, ventricular arrhythmias, or other severe heart conditions.Lidocaine may also be used to produce regional anesthesia (a loss of sensation in a specific region of the body for example, an arm or a leg or the entire pelvic region).May be combined with epinephrine which increases the intensity and duration of the anesthetic effect and constricts the blood vessels, reducing bleeding.The effect of lidocaine is almost immediate. Lidocaine prevents the transmission of pain impulses and is used as a local anesthetic to numb specific areas of the body before minor surgical, dental, or other procedures.Lidocaine belongs to the class of medicines known as class-1b antiarrhythmic drugs.This prevents the initiation and conduction of impulses along the nerve, which results in an anesthetic effect. Lidocaine works by blocking the influx of sodium ions into the membrane surrounding nerves.Lidocaine may be used as a local anesthetic or in the treatment of arrhythmias.Medically reviewed by Carmen Fookes, BPharm.
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